目的 :提高对药物性肝炎的认识。方法 :对216例药物性肝炎的发病规律及临床特征进行分析。结果 :药物性肝炎多发生于长期、联合使用有肝毒性的药物而又无肝功监测的患者 ,多见于农民及工人。多发生于服药后十天至一个月。有HBsAg阳性者更易发生药物性肝炎及重症肝炎 ,且病死亡率高。结论 :影响药物性肝炎的因素有患者的文化程度、药物的种类、用药时间、联合用药、HBsAg阳性、肝功能的监测等 Objective: To raise awareness of drug-induced hepatitis. Methods: The incidence and clinical characteristics of 216 cases of drug-induced hepatitis were analyzed. Results: Drug-induced hepatitis occurred in long-term, combined with hepatotoxic drugs without liver function monitoring, more common in farmers and workers. Occur in the medication after ten days to one month. HBsAg-positive who are more prone to drug-induced hepatitis and severe hepatitis, and the mortality rate is high. Conclusion: The factors influencing drug-induced hepatitis include patient’s education level, drug type, medication time, combination therapy, HBsAg positive, monitoring of liver function, etc.