机体的免疫系统对辐射很敏感,经照射后淋巴细胞的多种功能受到损伤,DNA合成减少使增殖能力下降是衡量细胞损伤程度的重要指标。IL-2有使免疫缺陷患者的免疫功能重建的作用,能使某些免疫抑制剂和辐射治疗造成的机体免疫功能降低得到逆转。本实验将正常人外周血淋巴细胞用递增剂量的γ射线照射,造成不同程度的损伤后,观察IL-2对其增殖抑制的逆转效应。 The body’s immune system is very sensitive to radiation, after irradiation, a variety of lymphocyte damage, DNA synthesis to reduce the proliferation ability is a measure of the degree of cell damage an important indicator. The role of IL-2 in reconstructing immune function in immunocompromised patients is to reverse some of the immunosuppressive effects of certain immunosuppressive agents and radiation-induced immunological dysfunction. In this experiment, the normal human peripheral blood lymphocytes with increasing doses of γ-ray irradiation, resulting in different degrees of damage, to observe the reversal effect of IL-2 on its proliferation inhibition.