血管内皮生长因子(vascular endothelial growth factor,VEGF)在肿瘤血管生成中起着非常重要的作用,它能够直接促进血管内皮细胞分裂增殖、分化、增生,与肿瘤的生长、浸润和转移有密切关系[1]。同样宫颈癌也存在血管生成[2],越来越受到人们的重视。本研究通过检测宫颈癌患者血清VEGF水平及mRNA表达,探讨其在宫颈癌诊断及评估预后中的临床意义。1对象与方法 Vascular endothelial growth factor (VEGF) plays a very important role in tumor angiogenesis. It can directly promote the proliferation, differentiation and proliferation of vascular endothelial cells and is closely related to tumor growth, invasion and metastasis [ 1]. The same cervical cancer also exists angiogenesis [2], more and more people’s attention. In this study, by detecting serum VEGF levels and mRNA expression in patients with cervical cancer, to explore its clinical significance in the diagnosis and prognosis of cervical cancer. 1 objects and methods