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目的:观察活血祛瘀类中药配伍结合西医治疗对慢性盆腔炎的疗效。方法:以2014年3月~2015年3月在我院接受治疗的80例慢性盆腔炎患者为观察对象,并将其随机分为对照组和观察组,每组各40例。对照组给予抗生素等西医治疗,观察组在此基础上给予活血祛瘀类中药配伍治疗,观察两组的治疗效果,比较两组治疗前后炎症细胞因子水平及血液流变学的变化。结果:观察组总有效率明显高于对照组,差别具有统计学意义;治疗前两组患者血常规及炎症因子水平无明显差别,治疗后两组WBC、NEU%、IL-6、hs-CRP和TNF-α均较治疗前降低,而观察组降低更为明显(P<0.05);两组治疗前血液流变学指标无明显差别,治疗后两组全血粘度、毛细管血浆粘度、全血还原粘度、红细胞聚集指数和纤维蛋白原水平均有所下降,而红细胞压积均有所升高,观察组上述指标改变较对照组更为明显。结论:活血祛瘀类中药配伍结合西医疗法可有效缓解炎症,对慢性盆腔炎有较好的治疗效果,可能与该疗法能改善患者的血液流变学特征有关。
Objective: To observe the curative effect of traditional Chinese medicine combined with western medicine in treatment of chronic pelvic inflammatory disease on traditional Chinese medicine of promoting blood circulation and removing blood stasis. Methods: Eighty patients with chronic pelvic inflammatory disease treated in our hospital from March 2014 to March 2015 were randomly divided into control group and observation group, 40 cases in each group. The control group was treated with antibiotics and other western medicine. On the basis of the above, the observation group was treated with traditional Chinese medicine of activating blood circulation and removing stasis, and the therapeutic effects of the two groups were observed. The levels of inflammatory cytokines and the changes of hemorheology were compared between the two groups. Results: The total effective rate in the observation group was significantly higher than that in the control group, the difference was statistically significant. There was no significant difference between the two groups in the blood levels and the levels of inflammatory cytokines. After treatment, the WBC, NEU%, IL-6, hs-CRP (P <0.05). There was no significant difference between the two groups in the indexes of hemorheology before treatment. After treatment, the whole blood viscosity, the capillary plasma viscosity, the whole blood Reduced viscosity, erythrocyte aggregation index and fibrinogen levels were decreased, while hematocrit increased, the observation group above indicators change more obvious than the control group. Conclusion: The traditional Chinese medicine combined with western medicine can effectively relieve the inflammation and has a better therapeutic effect on chronic pelvic inflammatory disease, which may be related to the improvement of the hemorheological characteristics of the patients.