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作者报道了47例原发性甲状旁腺功能亢进的外科治疗(1963～1985)。这些病人的特点是发病年龄较轻34.22±5.07岁(14～64岁);女:男比例为1.6:1;纤维囊性骨炎占78.7%,这是很突出的(47病人中有37例);血清钙值属于正常范围者占37.5%,有1/3病人有佝偻病及软骨病的某些特征。病理组织学检查除1例为腺癌者外,余均为腺瘤(1例曾疑诊为组织过度增生)。术前有14例病人有定位体征,11例可直接扪到肿物(1例为假阳性)。另外3例有间接定位体征,对于血清钙不升高的病人,其发病机制作了相应的讨论,作者着重指出外科医师在术中辨认病理改变的重要作用。
The authors reported 47 cases of primary hyperparathyroidism (1963-1985). These patients were characterized by a young age of onset 34.22±5.07 years (14 to 64 years); a female to male ratio of 1.6:1; fibrocystic osteitis accounted for 78.7%, which is very prominent (37 of 47 patients) ); serum calcium values are within the normal range of 37.5%, one-third of patients have some characteristics of rickets and rickets. Histopathological examination included 1 case of adenocarcinoma, and the rest were all adenomas (1 case had been suspected as hyperplasia of tissue). Before surgery, there were 14 patients with localized signs and 11 patients had direct access to the mass (1 case was false positive). The other 3 patients had indirect positioning signs. For the patients with no elevated serum calcium, the pathogenesis was discussed accordingly. The authors emphasized the important role of surgeons in identifying pathological changes during surgery.