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目的 探讨膜式液基薄层细胞学检测(ThinPrepcytologytest,TCT)技术在宫颈病变筛查中的价值。方法 对1747 例门诊及住院患者行TCT检测。细胞学检查阳性者行阴道镜检查及多点活检,并行病理组织学检查。结果 1747例中51例 不满意,不满意率2.92%,剩余1696例中1455例(85.79%)在正常范围内;139例(8.20%)为良性反应性改变;101例属非 典型鳞状上皮细胞(atypicalsquamouscells,ASC)及其以上病变,检出率5.96%,其中ASC52例(3.07%),鳞状上皮内病变 (squamousintraepitheliallesion,SIL)及鳞状细胞癌(squamouscellcarcinoma,SCC)共40例(2.36%),二者之比为1.30∶1;低度 鳞状上皮内病变(lowgradesquamousintraepitheliallesion,LSIL)33例(1.95%);高度鳞状上皮内病变(highgradesquamousin traepitheliallesion,HSIL)7例(0.41%);宫颈鳞状细胞癌(SCC)4例(0.24%)。不典型腺细胞(atypicalglandularcells,AGC)4 例(0.24%),腺癌(Adenocarcinoma1)4例(0.06%)。在微生物检测中,霉菌52例,检出率3.07%,滴虫4例,检出率0.24%。 与病理组织学对照,细胞学检出15例中的LSIL11例;检出7例HSIL中的6例;检出了全部4例鳞状细胞癌;组织学证实的1 例腺癌被检出。结论 TCT技术制作的薄片,细胞结构清晰,背景清朗,可明显提高标本的满意率;且?
Objective To investigate the value of ThinPrepcytology test (TCT) in the screening of cervical lesions. Methods 1747 outpatients and inpatients underwent TCT testing. Cytology positive colposcopy and multi-point biopsy, parallel histopathological examination. Results Among the 1747 patients, 51 were unsatisfactory and 2.92% unsatisfied. Among the remaining 1696 patients, 1455 (85.79%) were within the normal range, 139 (8.20%) were benign and were 101 patients with atypical squamous epithelium The prevalence of atypicalsquamous cells (ASC) and above lesions was 5.96%, including ASC52 (3.07%), squamous intraepithelial lesion (SIL) and squamous cell carcinoma (SCC) (1.95%) in low grade squamous intraepithelial lesion (LSIL); 7 cases (0.41%) of high grade squamous intraepithelial lesion (HSIL); Cervical squamous cell carcinoma (SCC) in 4 cases (0.24%). 4 cases (0.24%) of atypicalglandular cells (AGC) and 4 cases (0.06%) of adenocarcinoma (Adenocarcinoma1). In the detection of microorganisms, mold 52 cases, the detection rate was 3.07%, trichomoniasis in 4 cases, the detection rate was 0.24%. In contrast to the histopathology, 11 cases of LSIL were found in 15 cases cytologically; 6 cases were detected in 7 cases of HSIL; all 4 cases of squamous cell carcinoma were detected; and 1 case of adenocarcinoma confirmed by histology was detected. Conclusion TCT technique has the advantages of clear slice, clear cell structure and clear and bright background, which can obviously improve the satisfaction rate of specimens.