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脑啡肽是人体内由五十氨基酸组成的内源性吗啡样物质,其主要作用是调节痛觉,对激素分泌、呼吸体温调节、心血管生理变化、精神行为等也有一定影响,是目前国内外针麻和药理学研究的重要内容之一。上海市高血压研究所在脑组织和脑脊液的脑啡肽放射免疫测定法的基础上,最近又建立了血浆脑啡肽放射免疫测定法,从而为便于开展脑啡肽的临床研究提供了一种重要的手段。经过多种方法学的考证,该法灵敏(工作浓度1:20,000,最小检测量为5 pg),重复性好。临床上曾用此法测定嗜铬细胞瘤手术病人、精神分裂症、胰岛素休克治疗病人、电针治疗病人和运动员剧烈运动前后血中
Enkephalin is an endogenous morphine-like substance made up of fifty amino acids in the human body. Its main function is to regulate the pain and has some effects on the secretion of hormones, the regulation of respiratory thermoregulation, cardiovascular physiological changes and mental behaviors. It is currently used at home and abroad Acupuncture anesthesia and pharmacology one of the important content. Shanghai Institute of Hypertension in brain tissue and cerebrospinal fluid enkephalin radioimmunoassay, based on the recent establishment of a plasma enkephalin radioimmunoassay, which in order to facilitate the clinical study of enkephalin provides a Important means. After a variety of methodological research, the method is sensitive (working concentration of 1: 20,000, the minimum detection of 5 pg), good repeatability. Clinically, this method has been used to measure pheochromocytoma surgery patients, schizophrenia, insulin shock treatment of patients, electroacupuncture treatment of patients and athletes in the blood before and after vigorous exercise