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目的分析老年慢性阻塞性肺疾病(COPD)稳定期合并骨质疏松的易患因素。方法选取老年男性COPD稳定期患者120例,均行骨密度检测,并记录患者基本资料,分析老年COPD稳定期合并骨质疏松的易患因素。结果经骨密度检测发现,120例老年COPD稳定期患者中68例合并骨质疏松,30例骨量减少,22例骨量正常;三组患者吸烟指数、第1 s用力呼气容积占预计值百分比(FEV_1%Pre)、1 s用力呼气量占用力肺活量比值(FEV_1/FVC)和年龄比较,差异均无统计学意义(P>0.05);骨质疏松组COPD评估测试评分(CAT)明显高于骨量减少组和骨量正常组,体质量指数(BMI)、睾酮、维生素D水平均较低,差异有统计学意义(P<0.05)。结论 BMI、睾酮、维生素D水平均为COPD稳定期患者并发骨质疏松的易患因素,CAT评分越高预示骨质越差,将增加骨质疏松发生率。
Objective To analyze the predisposing factors for elderly patients with chronic obstructive pulmonary disease (COPD) with stable osteoporosis. Methods A total of 120 elderly patients with stable COPD were enrolled in this study. All patients were examined for bone mineral density (BMD) and the basic data of the patients were recorded. The susceptibility factors of elderly COPD with stable COPD were analyzed. Results The BMD of 68 COPD patients with stable COPD in the elderly group was found to be associated with osteoporosis, 30 with reduced bone mass, and 22 with normal bone mass. The smoking index and the forced expiratory volume at 1 s in the three groups accounted for the expected value (FEV_1% Pre), FEV 1 / FVC and age at 1 s had no significant difference (P> 0.05). The COPD score of the osteoporosis group was significantly higher than that of the control group Higher than the osteopenia group and normal bone mass group, body mass index (BMI), testosterone, vitamin D levels were lower, the difference was statistically significant (P <0.05). Conclusion The levels of BMI, testosterone and vitamin D are the predisposing factors for patients with stable COPD complicated by osteoporosis. The higher the CAT score is, the worse the bone quality will be, which will increase the incidence of osteoporosis.