脑瘫和社会经济学状况:一个回顾性队列研究

来源 :世界核心医学期刊文摘(儿科学分册) | 被引量 : 0次 | 上传用户:pluto529
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Aims: To study the relation between risk of cerebral palsy and socioeconomic s tatus. Methods: A total of 293 children with a diagnosis of cerebral palsy out o f 105 760 live births between 1 January 1982 and 31 December 1997 were identifie d from the special conditions sub-file of the West Sussex Computerised Child He alth System. Results: There was a linear association between risk of cerebral pa lsy and socioeconomic status (SES)-measured by the Registrar General’s social class (RGSC) and enumeration district (ED) ranked into quintiles by the Townsend Deprivation Index derived from 1991 census data. Fifty one per cent and 30%of cases of cerebral palsy were statistically “attributable”to inequality in SES using the RGSC and ED quintile respectively. A linear association was also noted for singleton live births. The association between risk of cerebral palsy and E D quintile persisted in a logistic regressionmodel that included birth weight an d gestational age, although that between RGSC and cerebral palsy no longer reach ed conventional levels of statistical significance after adjustment. Conclusions : A strong association was observed between socioeconomic status and the risk of cerebral palsy, which was only partly accounted for by the known social gradien ts in birth weight and gestational age. Aims: To study the relation between risk of cerebral palsy and socioeconomic s tatus. Methods: A total of 293 children with a diagnosis of cerebral palsy out of 105 760 live births between 1 January 1982 and 31 December 1997 were identifie d from the special conditions sub-file of the West Sussex Computerized Child Heal System. Results: There was a linear association between risk of cerebral pa lsy and socioeconomic status (SES) -measured by the Registrar General’s social class (RGSC) and enumeration district (ED) ranked into quintiles by the Townsend Deprivation Index derived from 1991 census data. Fifty one per cent and 30% of cases of cerebral palsy were statistically “attributable” to inequality in SES using the RGSC and ED quintile respectively. A linear association was also noted for singleton The association between risk of cerebral palsy and ED quintile persisted in a logistic regression model that included birth weight an d gestational age, although that betw een RGSC and cerebral palsy no longer reach ed conventional levels of statistical significance after adjustment. Conclusions: A strong association was observed between socioeconomic status and the risk of cerebral palsy, which was only partly accounted for by the known social gradien ts in birth weight and gestational age.
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