患儿,男,22天。因咳嗽10天,昏睡及全身皮肤发绀1小时人院。10天前患儿始有轻咳,渐呈阵发性顿咳,咳后呕吐,以晚上为重,不发热,吃奶及睡眠欠佳。经服各种止咳剂无效,于晚9时服可待因1/4片(每片15mg),服药后入睡,不咳。凌晨2时许发现患儿昏睡,全身皮肤发绀、呼吸微弱,急诊入院。患儿的兄患百日咳20余天,当地有百日咳流行。体检:体温36℃,脉搏150次,呼吸8次。发育营养中等,昏睡状,呼吸浅慢,不规则,全身皮肤发绀。前囱平,瞳孔针尖大小,对光反应消失。心、肺、腹部未见异常。化验:白细胞20,000,中性22%,淋巴78%。诊断:新生儿百日咳,急性可待因中毒。入院后即行人工辅助呼吸,吸氧,注射呼吸兴奋剂,补液,利尿及消炎等综合抢救治疗。于 Children, male, 22 days. Due to cough for 10 days, lethargy and systemic skin cyanosis 1 hour hospital. 10 days before the onset of mild cough in children, gradually paroxysmal sudden cough, cough and vomiting, night-heavy, no fever, poor feeding and sleep. After taking all kinds of cough suppressants ineffective at 9 o’clock in the evening taking codeine 1/4 (15mg per tablet), after taking medicine to sleep, not cough. At 2:00 am found that children with lethargy, systemic skin cyanosis, weak breathing, emergency admission. Children with brother and brother suffering from whooping cough more than 20 days, the local epidemic of whooping cough. Physical examination: body temperature 36 ℃, pulse 150 times, breathing 8 times. Moderately developed nutrition, drowsiness, breathing shallow, irregular, systemic skin cyanosis. Chimney before the pupil pinpoint size, disappeared on the light response. Heart, lung, abdomen no exception. Laboratory: WBC 20,000, 22% neutral, lymphatic 78%. Diagnosis: newborn whooping cough, acute codeine poisoning. After admission, artificial ventilation, oxygen inhalation, respiratory stimulants, fluid replacement, diuretic and anti-inflammatory comprehensive rescue treatment. in