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目的 探索胃癌病人淋巴结转移个数及率与胃癌病人预后以及病理参数之间的关系。方法 对 174例有淋巴结转移的胃癌病人行胃癌根治术加D2 或D3 淋巴结清扫 ,分析淋巴结转移阳性个数、率、部位与预后及病理参数之间的关系。结果 胃癌根治术后 (D2 、D3) 5年生存率为 2 9.5 9% (5 0例 )。阳性淋巴结个数为 1～ 5个 5年生存率为 46 .47% (33例 ) ,大于 5个的为 17.35 % (17例 ) (P <0 .0 0 5 ) ;阳性淋巴结率在 1%～ 2 0 %的 5年生存率为 70 .5 8% ,2 0 %以上 5年生存率为 11.86 %。 5年生存率随着阳性淋巴结个数、率增多而呈下降趋势。随着肿瘤浸润加深 ,淋巴结转移个数、率增高 (P <0 .0 0 5 )。结论 胃癌转移淋巴结状态与胃癌病人预后有相关性 ,胃癌转移淋巴结个数、转移率可作为简单、有效的预后指标
Objective To explore the relationship between the number and rate of lymph node metastasis and the prognosis and pathological parameters of gastric cancer patients. Methods 174 patients with gastric cancer with lymph node metastasis underwent radical gastrectomy plus D2 or D3 lymph node dissection. The relationship between the number of positive lymph node metastases, rate, location and prognosis and pathological parameters was analyzed. Results The 5-year survival rate after radical gastrectomy (D2, D3) was 29.59% (50 cases). The number of positive lymph nodes was 1 to 5 with a 5-year survival rate of 46.47% (33 cases), and greater than 5 were 17.35% (17 cases) (P < 0.05); positive lymph node rate was 1% The 5-year survival rate of ~ 20% is 70.58%, and the 5-year survival rate is above 20% and 11.86%. The 5-year survival rate showed a downward trend with the increase in the number and rate of positive lymph nodes. With the deepening of tumor invasion, the number and rate of lymph node metastasis increased (P < 0.05). Conclusions The metastasis status of gastric cancer is related to the prognosis of gastric cancer patients. The number and metastasis rate of metastatic lymph nodes in gastric cancer can be used as simple and effective prognostic indicators.