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目的观察降压药物小剂量联合治疗高血压降压达标效果。方法将63例中重度高血压患者随机分为对照组(A组,依那普利)、B组(得高宁)和联合治疗组(C组,依那普利+得高宁),对照组常规剂量,联合治疗组小剂量,治疗4周,观察血压达标情况及药物不良反应。结果小剂量联合治疗组降压达标明显优于对照组,且不良反应少。结论得高宁依那普利小剂量联合治疗中重度高血压疗效肯定,值得临床应用。
Objective To observe the efficacy of antihypertensive drugs in combination with low-dose antihypertensive drugs. Methods Sixty-three patients with moderate-to-severe hypertension were randomly divided into control group (group A, enalapril), group B (dipyridamole) and combination therapy group (group C, enalapril + dipyridamole) Group conventional dose, low dose combination therapy group for 4 weeks, observe the blood pressure compliance and adverse drug reactions. Results Low-dose combination treatment group markedly lower blood pressure was significantly better than the control group, and fewer adverse reactions. Conclusion High-dose enalapril combined with low-dose treatment of moderate and severe hypertension affirmation, it is worth clinical application.