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Primaxin为注射用干粉针，其中含亚胺培南（I）和西司地丁（II）各500mg碳酸氢钠20mg。将其溶于100ml生理盐水或其它输液中，制成5mg／ml，供静脉输注用。本文介绍一阶导数光谱法在243和318nm处同步测定此制剂中的I和II的含量。方法快速、精密和准确，适用于常规的释放度试验.?
Primaxin is a dry powder injection for injection containing 20 mg of 500 mg sodium bicarbonate each containing imipenem (I) and cilastatin (II). It is dissolved in 100 ml of normal saline or other infusion, made of 5mg / ml for intravenous infusion. This article describes first-order derivative spectroscopy for simultaneous determination of I and II in this formulation at 243 and 318 nm. The method is fast, precise and accurate and suitable for routine release tests.