东南亚某些地区维生素Ｂ１缺乏症（脚气病）常见。急性维生素Ｂ１缺乏症酷似疟疾的许多并发症，例如脑病、低血糖与乳酸中毒。严重疟疾患者中有关维生素Ｂ１缺乏及其后发病的研究尚未见报道。本文报道泰国疟疾住院成人中维生素Ｂ１缺乏症发病率的一项前瞻性研究结果。受试对象 Vitamin B1 deficiency (beriberi) is common in some parts of Southeast Asia. Acute vitamin B1 deficiency resembles many of the complications of malaria, such as encephalopathy, hypoglycemia and lactic acidosis. Research on vitamin B1 deficiency and subsequent morbidity in patients with severe malaria has not been reported. This article reports the results of a prospective study of the incidence of vitamin B1 deficiency in hospitalized adults in malaria in Thailand. Subjects