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目的:探讨纳米碳示踪剂引导腹腔镜进展期胃癌淋巴结清扫的应用价值。方法:31例实施纳米碳示踪下腹腔镜淋巴结清扫为研究组;同期行传统腹腔镜胃癌手术26例及抽样分析3 a来行传统开腹手术的进展期胃癌68例作为对照组,比较三组清扫淋巴结的数目和0.5 a生存率。结果:研究组均满意黑染区域淋巴结,切除数目显著多于传统腹腔镜组手术组(P<0.05);与传统开腹手术组切除淋巴结数目无统计学差异(P>0.05)。淋巴结转移阳性率:实验组69.8%,传统腹腔镜组44.8%(P<0.05),传统开腹手术组56.5%(P>0.05)。0.5 a复发率:研究组5.6%,对照组分别是26.9%和7.3%(P<0.05)。结论:纳米碳示踪剂引导腹腔镜胃癌淋巴结清扫可有助于术中辨认淋巴结,增加清扫数目,与传统开腹淋巴清扫效果相当。
Objective: To investigate the value of nanocarbon tracer in guiding lymphadenectomy of advanced gastric cancer with laparoscopy. Methods: Thirty-one patients underwent laparoscopic lymph node dissection with carbon-carbon nanotubes as the study group. Sixty-six patients with conventional laparoscopic gastric cancer surgery during the same period and 68 patients with advanced gastric cancer undergoing conventional laparotomy were sampled as the control group. The number of dissected lymph nodes and 0.5-year survival rate. Results: The study group was satisfied with the black stained lymph nodes, the number of resections was significantly more than that of the conventional laparoscopic surgery group (P <0.05). There was no significant difference in the numbers of resected lymph nodes between the two groups (P> 0.05). The positive rate of lymph node metastasis was 69.8% in the experimental group, 44.8% in the traditional laparoscopic group (P <0.05), and 56.5% in the traditional laparotomy group (P> 0.05). 0.5 a Recurrence rate: 5.6% in study group and 26.9% and 7.3% in control group (P <0.05). Conclusion: Nano-carbon tracer guided laparoscopic lymph node dissection of gastric cancer can help identify lymph nodes, increase the number of cleaning, with the traditional open laparoscopic lymph node dissection effect.