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目的 评价铅对其作业女工子代神经行为的影响。方法 对某冶炼厂职工子弟学校学生的母亲孕前至调查时从事铅作业的 94名 1～ 4年级小学生 ( 6～ 10岁 )作为接触组和无铅污染的农村小学 94名学生作对照 ,其年龄、性别、年级、家庭情况两组基本相同。用原子吸收光谱测定血铅 ;用ZPP 2 0 0 0荧光仪测定锌卟啉 ;用WHO推荐的神经行为核心测试组合 (NCTB)测定神经行为功能 ;用高压液相 ,134 0型电化学仪测定尿中HVA、VMA ;所有数据用SPSS软件作t检验。结果 血铅、血锌卟啉、血红蛋白、红细胞总数和尿中HVA及VMA等指标两组有非常显著的差别 (P <0 0 1)。行为功能数字跨度 (顺序 )得分 ,接触组显著低于对照组 (P <0 0 5) ,简单反应时最快值、数字跨度总和及数字跨度 (倒序 )得分接触组非常显著低于对照组 (P <0 0 1)。结论 铅对作业女工子代神经行为有不良影响
Objective To evaluate the effect of lead on the neurological behavior of female laborers in their homework. Methods A total of 94 primary schoolchildren aged from 1 to 4 (6 to 10 years old) engaged in lead work during the pre-pregnancy and post-pregnancy surveys of mothers of school children of a smelter were compared with 94 students from rural primary school without lead pollution. The age , Gender, grade, family situation is basically the same in both groups. Blood lead was determined by atomic absorption spectrometry. Zinc porphyrin was measured by ZPP 2000 spectrophotometer. Neurobehavioral function was determined by the WHO core behavioral test set (NCTB). The high pressure liquid phase and 134 0 electrochemistry Urinary HVA, VMA; all data using SPSS software for t test. Results There were significant differences between the two groups (P <0.01), such as blood lead, blood zinc porphyrin, hemoglobin, total number of red blood cells and HVA and VMA in urine. The score of behavioral function was significantly lower in the contact group than in the control group (P <0 05), the value of the simplest response time, the sum of the number of spans and the numerical span (reverse order) score of the contact group were significantly lower than those of the control group P <0 0 1). Conclusion Lead has adverse effects on female workers’ generation of neurons