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15例诊断为白血病前期的患者用G—带染色法检查了染色体的改变。发现9例的染色体完全正常,其他6例有各种染色体异常。染色体数异常有5例三体性;结构异常有1例缺失和1例标记染色体。全部6例有C 组异常,3例A 组异常,G—带法显示三体C 涉及8号染色体(2例)和9号(3例);1例缺失染色体证明为11(11q—),1例标记染色体来源于染色体3与6的易位。A 组异常涉及3号染色体。用G—带法所检查见的异常染色体与以往在急性白血病中发现
Fifteen patients diagnosed with pre-leukemia were examined for chromosome changes using G-band staining. Chromosomes found in 9 cases completely normal, the other 6 cases have a variety of chromosomal abnormalities. There were 5 cases of chromosomal abnormalities trisomy; 1 case of structural abnormalities and 1 case of missing chromosome markers. All 6 patients had abnormalities in group C and 3 patients in group A were abnormal. G-banding showed that trisomy C involved chromosome 8 (2 cases) and 9 (3 cases). One case of deletion chromosome was 11 (11q-) One case of marker chromosome was derived from the translocation of chromosomes 3 and 6. A group of abnormalities involving chromosome 3. Abnormal chromosomes examined with G-banding were found in previous acute leukemias