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目的观察双环醇与多烯磷脂酰胆碱治疗酒精性肝病的临床效果差异。方法选取酒精性肝病患者80例,随机分成观察组和对照组两组各40例,观察组采用双环醇治疗酒精性肝病,对照组采用多烯磷脂酰胆碱治疗酒精性肝病,治疗周期均为36周,然后对两组结果进行比较。结果观察组完全应答率为55%,部分应答率为35%,对照组完全应答率为50%,部分应答率为20%,观察组治疗效果比对照组显著(P<0.05),具有统计学意义。结论双环醇在改善肝功能ALT、GGT和肝纤维化方面要比多烯磷脂酰胆碱效果显著。
Objective To observe the clinical effects of bicyclic alcohol and polyene phosphatidylcholine in the treatment of alcoholic liver disease. Methods Eighty alcoholic liver disease patients were randomly divided into observation group and control group, 40 cases in each group. The observation group was treated with bicyclol for alcoholic liver disease. The control group was treated with polyene phosphatidylcholine for alcoholic liver disease. The treatment cycles were 36 weeks, and then compare the two groups of results. Results The complete response rate was 55%, the partial response rate was 35% in the observation group, the complete response rate was 50% and the partial response rate was 20% in the observation group. The treatment effect in the observation group was significantly higher than that in the control group (P <0.05) significance. Conclusion Bicyclol is more effective than polyene phosphatidylcholine in improving liver function ALT, GGT and liver fibrosis.