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川芎嗪是从川芎中提取分离出的生物碱,是一种新型钙离子拮抗剂和自由基清除剂,临床广泛应用于治疗缺铁性心血管疾病,近年来国内有文献报道其不良反应,现概述如下:1过敏反应孔戴艳报道,患女,60岁,因心肌缺血给予川芎嗪葡萄糖注射液0.8克静滴,滴完2小时后患者自觉心慌,欲吐,伴有呛咳,1小时后逐渐恢复正常。次日静滴本品,1小时后右手肘部内侧皮肤出现红肿,瘙痒,伴心慌,停药后未出现上述症状[1]。
Ligustrazine is extracted from the Ligusticum chuanxiong alkaloids, is a new type of calcium ion antagonist and free radical scavenger, clinical widely used in the treatment of iron deficiency cardiovascular disease in recent years, the domestic literature reports its adverse reactions, and now Summarized as follows: 1 allergic reaction Kong Dai Yan reported that suffering from female, 60 years old, due to myocardial ischemia give tetramethylpyrazine 0.8g intravenous infusion of glucose injection, 2 hours after the end of the patient consciously palpitation, vomiting, accompanied by cough, 1 Gradually returned to normal after hours. The next day intravenous infusion of this product, 1 hour after the right elbow skin irritation, itching, with palpitation, did not appear after stopping the above symptoms [1].