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目的:介绍辅料在口服结肠靶向制剂中的应用,为更深入的研究提供参考。方法:通过查阅国内外大量相关文献,对常用于口服结肠靶向制剂的几种辅料及其相应的释药系统进行分析概述。结果:辅料是药物制剂的基础材料和重要组成部分,在口服结肠靶向制剂的发展和生产中起关键作用。结论:辅料的选择对制剂的结肠定位起至关重要的作用。
OBJECTIVE: To introduce the application of excipients in oral colon targeted preparations and provide reference for further research. Methods: By referring to a large number of relevant literature at home and abroad, several excipients and their corresponding drug release systems commonly used in oral colon-targeted preparations were analyzed and summarized. Results: Excipients, the basic material and an important component of pharmaceutical preparations, play a key role in the development and production of oral colon-targeted preparations. Conclusion: The choice of excipients plays a crucial role in the colon localization of the preparation.