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目的评价苏州大学附属儿童医院新生儿重症监护室(NICU)早产儿出生时宫内生长发育迟缓(intrauterine growth restriction,IUGR)和出院时宫外生长发育迟缓(extrauterine growth restriction,EUGR)的发生比例,并评估EUGR的危险因素。方法对本院NICU126例早产儿病例资料进行回顾性分析,对其宫内、宫外生长发育迟缓的发生比例进行统计,并通过Logistic回归分析对相关危险因素进行评估。结果 126例早产儿出生时IUGR的比例为29.37%,出院时EUGR的比例占27.78%,其中SGA早产儿EUGR发生比例达54.05%。Logistic回归分析表明,与EUGR有关的高危因素包括出生胎龄小、低出生体重以及合并并发症等。结论 NICU中早产儿IUGR、EUGR的发生比例仍较高。对其采取正确的、积极的早期营养支持,并防治早产儿常见合并症,对减少EUGR的发生、提高其生存质量意义重大。
Objective To evaluate the incidence of intrauterine growth restriction (IUGR) and extrauterine growth restriction (EUGR) in neonates with neonatal intensive care unit (NICU) at Children’s Hospital Affiliated to Soochow University, And assess the risk factors of EUGR. Methods A retrospective analysis was performed on 126 cases of premature infants with NICU in our hospital. The incidence of intrauterine and extrauterine growth retardation were statistically analyzed. Logistic regression analysis was used to evaluate the risk factors. Results The percentage of IGRs in 126 preterm infants was 29.37% at birth and 27.78% at EUGR. The proportion of EUGR in preterm infants with SGA was 54.05%. Logistic regression analysis showed that the high risk factors associated with EUGR include small gestational age at birth, low birth weight and complications. Conclusion The incidence of IUGR and EUGR in NICU is still high. To take correct and positive early nutritional support and prevention and treatment of common comorbidities in preterm children is of great significance to reduce the occurrence of EUGR and improve its quality of life.