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目的 :分析引起药物不良反应 (ADRs)的相关因素。方法 :对北京石景山区ADRs监察网内 4所医院自 1996年 8月~ 1998年 12月间收集的 112例ADRs报告进行统计分析。结果 :112例ADRs报告中最易引起药物不良反应的药物为抗感染药物 ,占 75例 (6 7% ) ;皮肤、粘膜反应 5 7例 (5 0 .9% ) ;住院患者 80例 (71.4% ) ;注射给药 82例 (73.2 % ) ;合并用药 92例 (82 .1% ) ;6 1岁以上患者 39例 (34 .8% )。结论 :药物不良反应的发生与多种因素有关
Objective: To analyze the related factors that cause adverse drug reaction (ADRs). Methods: A total of 112 ADRs collected from 4 hospitals in ADRs monitoring network in Shijingshan District of Beijing from August 1996 to December 1998 were analyzed statistically. Results: Among the 112 ADRs reported, the most susceptible drugs were anti-infectives, accounting for 75% (67%), skin and mucosal reactions (57.9%), hospitalized patients (71.4% %); 82 cases (73.2%) were administered by injection; 92 cases (82.1%) were combined with medication; 39 cases (34.8%) were over 6 years old. Conclusion: The incidence of adverse drug reactions and a variety of factors