甲硝唑已广泛用于治疗或预防厌氧菌引起的系统或局部感染。其口服吸收好 ,在体内分布广泛 ,可进入唾液、乳腺、肝脓疡的脓液中 ,也可进入脑脊液 [1 ] 。但在使用过程中 ,出现了的大量不良反应 ,应引起临床的高度重视。本文检索 1982～1998年部分医学期刊的相关报道 ,综述如下。 Metronidazole has been widely used to treat or prevent systemic or local infections caused by anaerobic bacteria. Its oral absorption is good, widely distributed in the body, can enter the saliva, breast, liver abscess pus, can also enter the cerebrospinal fluid [1]. However, during use, a large number of adverse reactions have emerged, which should arouse clinical attention. This article searches for some reports of some medical journals from 1982 to 1998, which are summarized as follows.