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为了观察防风有无抗凝作用,给小鼠腹腔注射防风正丁醇萃取物后测定了凝血时间和出血时间。结果,用玻片法测得的凝血时间,生理盐水组为0.6±0.2min,而防风8g/kg组为1.7±1.0min(P<0.001),4g/kg组为1.3±1.0min(P<0.01):用毛细管法测得的凝血时间,生理盐水组为1.6±0.6min,防风组分别为2.9±1.0min(P<0.001)和2.2±0.8(P<0.05);用断尾法测得的出血时间,生理盐水组为12.6±4.8min,防风组分别为17.3±5.6min(P<0.01)和16.1±3.0min(P<0.01).结果提示防风正丁醇萃取物有明显的抗凝作用。
In order to observe whether the wind has anticoagulant effect, the clotting time and bleeding time were measured after intraperitoneal injection of the wind-proof n-butanol extract. As a result, the clotting time measured by the slide method was 0.6±0.2 min in the saline group and 1.7±1.0 min in the wind-resistant 8 g/kg group (P<0.001), 4 g/kg group. 1.3±1.0 min (P<0.01): The clotting time measured by the capillary method was 1.6±0.6 min in the saline group and 2.9±1.0 min in the wind shield group (P<0.05). <0.001) and 2.2±0.8 (P<0.05); the bleeding time measured by the tail-breaking method was 12.6±4.8 min in the saline group and 17.3 in the windbreak group, respectively. ±5.6 min (P<0.01) and 16.1±3.0 min (P<0.01). The results suggest that the butanol extract has a significant anticoagulant effect.