论文部分内容阅读
目的:探讨慢性扁桃体炎患者是否存在早期肾损害。方法:77例慢性扁桃体炎患者按病程分为3组,A组:病程1～3年,B组:病程>3～5年,C组:病程>5年;另选20例健康志愿者为对照组。采用酶联免疫吸附法(ELISA)进行尿微量白蛋白测定并取其均值作比较,并对其中获随访的19例慢性扁桃体炎患者手术治疗前、后的尿微量白蛋白含量进行比较。结果:①A、B、C组尿微量白蛋白值分别为(9.8±1.6)mg/L、(12.3±2.2)mg/L、(17.6±3.2)mg/L,对照组为(9.6±2.0)mg/L,C组明显高于对照组(P<0.05)。②19例获随访的慢性扁桃体炎患者手术治疗前、后的尿微量白蛋白值分别为(26.3±2.2)mg/L和(18.7±1.7)mg/L(P<0.05)。结论:慢性扁桃体炎患者随病程的增长其尿微量白蛋白有排泌增加的趋势;尿微量白蛋白的检测可以列为慢性扁桃体炎早期肾损害的参考诊断指标之一;其检测对慢性扁桃体炎手术疗效评价具有重要意义。
Objective: To investigate whether there is early renal damage in patients with chronic tonsillitis. Methods: Totally 77 patients with chronic tonsillitis were divided into 3 groups according to their course of disease: group A: duration of 1-3 years; group B: duration of 3-5 years; group C: duration of disease> 5 years; 20 healthy volunteers Control group. The microalbuminuria was measured by enzyme-linked immunosorbent assay (ELISA), and the mean value was compared. The urine microalbumin contents of 19 chronic tonsillitis patients who were followed up before and after operation were compared. Results: The urinary albumin values in group A, B and C were (9.8 ± 1.6) mg / L and (12.3 ± 2.2) mg / L and (17.6 ± 3.2) mg / mg / L, C group was significantly higher than the control group (P <0.05). ② The urine microalbuminuria of 19 patients with chronic tonsillitis who were followed up before and after operation were (26.3 ± 2.2) mg / L and (18.7 ± 1.7) mg / L respectively (P <0.05). CONCLUSIONS: Patients with chronic tonsillitis tend to have increased excretion of urinary albumin as the disease progresses. The detection of urinary microalbuminuria may be one of the reference diagnostic indicators of early renal damage in chronic tonsillitis. The detection of chronic microalbuminuria Evaluation of the efficacy of surgery is of great significance.