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目的 BEOD方案是治疗何杰金氏病较好方案。我们对1989年11月～1997年5月我科收治晚期复发常规化疗无效何杰金氏病人42例用BEOD方案治疗后进行回顾性分析,以便了解完全缓解率、总有效率。并与目前报导相比较。方法 42例病人均采用BEOD方案化疗2周期以上。结果 完全缓解(CR)26例,占61.9％。部分缓解(PR)8例,占19％。有效率(RR)34例,占80.9％。结论 本方案对晚期复发常规化疗无效病例完全缓解率明显高于CEP方案。总有效率高于目前报导。因此治疗晚期复发常规化疗无效何杰金氏病,该方案仍为较好的化疗方案。
Objectives The BEOD protocol is a better treatment for Hodgkin’s disease. We conducted retrospective analysis of 42 cases of Hodgkin’s patients treated with late-onset relapsed conventional chemotherapy in our department between November 1989 and May 1997 in order to understand the complete remission rate and total effective rate. And compared with the current report. Methods 42 patients were treated with BEOD regimen for more than 2 cycles. Results Complete remission (CR) occurred in 26 cases, accounting for 61.9%. Partial remission (PR) occurred in 8 cases, accounting for 19%. Effectiveness (RR) was 34 cases, accounting for 80.9%. Conclusions The complete remission rate of this protocol in patients with advanced relapsed conventional chemotherapy is significantly higher than that of CEP. The total efficiency is higher than the current report. Therefore, the treatment of late recurrence of conventional chemotherapy is ineffective in Hodgkin’s disease, this program is still a good chemotherapy program.