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目的探讨血清磷脂脂肪酸与肥胖的关系,为指导肥胖儿童进行饮食干预提供依据。方法分别抽取肥胖儿童41例和健康儿童40例,采用国际标准气相色谱法测定血清磷脂脂肪酸谱,用SPSS13.0统计软件进行统计学处理。结果肥胖儿童血清磷脂脂肪酸谱与健康对照组差异有统计学意义。肥胖儿童SFA,C16:0,C16:1,C18:0,C18:3n-6,C18:3n-3,C20:0,C20:2n-6,C20:3n-6,C22:1,C16:1/C16:0,C20:3n-6/C18:2n-6显著高于健康对照组;PUFA,n-6PUFA,PUFA/SFA,C14:0,C18:1n-7,C18:2n-6,C20:1,C20:4n-6,C20:4n-6/C20:3n-6显著低于健康对照组(P值均<0.05)。结论重视儿童膳食脂肪酸摄入组成,增加膳食中PUFA尤其是n-3PUFA的摄入,减少SFA摄入,预防儿童肥胖及肥胖相关性疾病,具有重要意义。
Objective To explore the relationship between serum phospholipid fatty acid and obesity and provide the basis for dietary intervention in obese children. Methods 41 cases of obese children and 40 healthy children were selected respectively. The serum phospholipid fatty acid profiles were determined by international standard gas chromatography, and the data were analyzed by SPSS13.0 statistical software. Results The serum phospholipid fatty acid profiles in obese children were significantly different from those in healthy controls. Obese children SFA C16: 0 C16: 1 C18: 0 C18: 3n-6 C18: 3n-3 C20: 0 C20: 2n-6 C20: 3n-6 C22: 1 C16: 1 / C16: 0, C20: 3n-6 / C18: 2n-6 was significantly higher than that of the healthy control group; PUFA, n-6 PUFA, PUFA / SFA, C14: 0, C18: C20: 1, C20: 4n-6 and C20: 4n-6 / C20: 3n-6 were significantly lower than those in healthy controls (all P <0.05). Conclusion It is of great significance to pay attention to the composition of dietary fatty acid intake in children, increase the intake of dietary PUFA, especially n-3PUFA, reduce the intake of SFA and prevent childhood obesity and obesity-related diseases.