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过敏性休克致死者常规尸检未能发现特异性病理改变,生化检测尚缺乏客观特异性诊断指标,因此,寻求客观特异性生化诊断指标以明确诊断过敏性休克致死案件,成为法医学死因鉴定迫切需要解决的一大难题。本文通过对趋化因子(Eotaxin、IL-5、IL-8等)及其受体研究进展的综述,试图从生化角度阐述趋化因子及其受体作为过敏性休克的特异诊断性指标可能性及其研究进展,为目前法医学过敏性休克死亡生化检测提供新的研究思路。
The routine autopsy of anaphylactic shock failed to find the specific pathological changes, the biochemical test is still lack of objective and specific diagnostic indicators, therefore, to seek objective and specific biochemical diagnostic indicators to diagnose a case of anaphylactic shock and death, a forensic cause of death identified an urgent need to resolve A big problem In this review, we summarize the progress of chemotactic factors (Eotaxin, IL-5, IL-8, etc.) and their receptors, and attempt to elucidate the possibility of using chemokines and their receptors as specific diagnostic indicators of anaphylactic shock And its research progress, provide a new research idea for the biochemical detection of the death of anaphylactic shock in forensic medicine.