硬皮病是难治之证。笔者用温肾养血、健脾益气,疏通经络的治疗原则,以归脾汤加减治疗1例,获得较好效果,兹介绍如下。韦某,女,41岁,农民,1980年8月4日就诊。患者右腹皮肤发硬近1年。曾在某医院诊为过敏性皮炎或局限性硬皮病,用激素、中药等治疗无效,局部皮肤紧迫感日益严重,弯腰困难。症见右胁下脐旁3cm 处有一皮肤硬块,面积为12.5×8cm,色呈暗褐色,表面无皱纹呈腊样,手捏不起。每遇寒冷天气,硬肿局部皮肤变紫暗色,麻木疼痛加剧,四肢冰凉,脚趾亦有麻木感,尚伴有 Scleroderma is refractory evidence. The author used Wenshen nourishing, spleen Qi, dredge the meridians of the principle of treatment, with Guipi Decoction treatment in 1 case, to obtain better results, are described below. Wei Mou, female, 41 years old, farmer, treated on August 4, 1980. The right abdomen skin hardened nearly 1 year. In a hospital diagnosed with allergic dermatitis or localized scleroderma, treatment with hormones, herbs, etc. was ineffective. The local skin sensation became more and more serious and it was difficult to bend over. Zheng Jian see the right flank 3cm next to the umbilicus with a skin lump, an area of ​​12.5 × 8cm, dark brown color, no wrinkles on the surface were wax-like, hand pinch can not afford. In case of cold weather, the hard swollen part of the skin becomes dark purple, the pain in numbness increases, the limbs become cold, and the toes also have numbness.