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目的：探讨应用宫腔镜下输卵管插管局部注射甲氨蝶呤对于输卵管妊娠患者的疗效，分析影响因素。方法：回顾分析吉林市妇产医院2008年2月至2011年2月确诊输卵管妊娠患者86例，应用宫腔镜，将50毫克甲氨蝶呤局部注射至患侧输卵管，同时口服中药，观察血HCG下降及盆腔包块减小情况。结果：临床治愈率83．7％（72／86）；4例在一周后复查血HCG升高，行第二次宫腔镜下局部注射治疗；5例因宫腔内粘膜下肌瘤或子宫内膜息肉，无法局部注射，改为腹腔镜下手术；5例治疗失败。3个月后对66例行宫腔镜下输卵管插管局部注射甲氨蝶呤治愈的患者随访，其中月经恢复正常的有55例（83．3％）。结论：宫腔镜下输卵管插管局部注射甲氨蝶呤治疗异位妊娠的效果明显，具有简便易行的特点，是可行的有效的方法。“,”Objective TO investigate the efect of Methotrexate(MTX)injection by hysteroscopic tubal catheterization for tubal pregnancy ,and to analyse factors influencing curative ef ects of such approach.Methods:Retrospectively analyze 86 cases with tubal pregnancy treated by hysteroscopic tubal catheterization underwent injection of MTX 50mg ,from February 2008 to February 2011 in Jilin Maternity Hospital,take traditional Chinese medicine at the same time,then observe the drops of HCG and the degree of seniority of the swel ing.Results:The cure rate was 83.7%(72/86),4 cases are injected by hysteroscopic once more after one week and the serum β-HCG ascend;because of submucous myoma or polyp,5 cases can not be injected by hysteroscopic change laparoscopic surgery;5 cases fail.Out of the 66 cured patients fol owed up for three months,55(83.3%)get normal menstruation.Conclusion:MTX injection by hystero-scopic tubal catheterization for tubal pregnancy is ef ective and simple ,which is a ideal surgery method.