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以非病区粮对照、克山病病区粮及其添加豆油(60g豆油/kg饲料)饲料喂养大鼠70d,测定各组织中维生素E及血浆中脂质过氧化物含量。结果显示:无论是病区粮饲料组,还是非病区粮饲料组,在饲料中添加豆油后,动物血浆中α-生育酚(α-Tocopherol)含量均增加,而心肌线粒体中α-Tocopherol含量则下降,肝线粒体中α-Tocopherol和γ-Tocopherol含量均下降,红细胞膜中α-Tocopherol含量亦有降低趋势。另外,饲料中长期添加豆油,可使大鼠血浆中脂质过氧化物含量显著增加。说明,随着多不饱和脂肪酸(PUFAs)摄入量的增加,膜系统α-Tocopherol的消耗量亦增加,PUFAs长期负荷,可使饲克山病病区粮(低硒低维生素E)饲料动物体内的抗氧化能力下降。
The non-ward food control, Keshan disease ward and its added soybean oil (60g soybean oil / kg feed) feed 70d rats were measured in each tissue vitamin E and plasma lipid peroxidation levels. The results showed that α-Tocopherol content in plasma of animals was increased, while α-Tocopherol content in myocardial mitochondria The content of α-Tocopherol and γ-Tocopherol in liver mitochondria decreased and the content of α-Tocopherol in erythrocyte membrane also decreased. In addition, the long-term feed soybean oil, can rat plasma lipid peroxide levels increased significantly. The results showed that with the increase of polyunsaturated fatty acids (PUFAs) intake, the consumption of membrane system α-Tocopherol also increased, and the long-term load of PUFAs could make the food (low selenium and low vitamin E) The body’s antioxidant capacity decreased.