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目的:动态观察尼莫地平对高血压脑出血患者局部脑血流及其临床疗效的影响。方法:随机将69例高血压脑出血患者分为对照组和尼莫地平治疗组,并行SPECT和临床疗效的动态观察。图像的处理和临床疗效的评定采用盲法分析。结果:治疗组在SPECT和临床疗效的改善方面显著优于对照组。结论:尼莫地平可改善高血压脑出血后的局部脑血流下降和伴随的临床变化。
Objective: To dynamically observe the effect of nimodipine on regional cerebral blood flow in patients with hypertensive intracerebral hemorrhage and its clinical effect. Methods: A total of 69 patients with hypertensive intracerebral hemorrhage were randomly divided into control group and nimodipine treatment group. The dynamic observation of concurrent SPECT and clinical efficacy was performed. Image processing and evaluation of clinical efficacy using blind analysis. Results: The treatment group was significantly better than the control group in the improvement of SPECT and clinical efficacy. Conclusion: Nimodipine can improve the local cerebral blood flow decline and the accompanying clinical changes after hypertensive intracerebral hemorrhage.