干燥综合征是一种以口眼干燥为特征,主要累及外分泌腺的弥漫性结缔组织病。其发病可能与病毒感染、遗传和性激素异常等多种因素有关,在这些因素的共同作用下,机体免疫异常,组织损伤。与该病关系较密切的病毒有EB病毒、丙型肝炎病毒、巨细胞病毒、反转录病毒等。病毒在干燥综合征的发病机制中可能起重要的作用。 Sjogren’s syndrome is characterized by dry mouth and mouth, mainly involving the exocrine gland diffuse connective tissue disease. The incidence may be related to viral infection, genetic and sex hormone abnormalities and other factors related to the combination of these factors, the body immune dysfunction, tissue damage. Viruses associated with the disease are EB virus, hepatitis C virus, cytomegalovirus, retrovirus and so on. The virus may play an important role in the pathogenesis of Sjogren’s syndrome.