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本文用无火焰原子吸收分光光度仪ＨＩＴＡＣＨＩ－１８０测试置ＶＣｕ２００ＩＵＤ妇女宫颈粘液含铜量２６７例。其结果为自第１年平均含铜量２．６６±０．５８μｇ／ｇ粘液湿重至第１５年降为０．９１±０．６μｇ／ｇ粘液湿重，显示宫颈粘液含铜量随放置时间延长而渐减少。金属圆环组２１４例，各不同年限宫颈粘液含铜量平均为０．３５±０．０８～０．５６±０．１４μｇ／ｇ粘液湿重。未带器组２１例宫颈粘液平均含铜量为０．４７±０．１１μｇ／ｇ粘液湿重，ＶＣｕ２００组与金属圆环组各年限相比均有显著差异（Ｐ＜０．０５～０．００１）。与未带器组比各年ｆＫ亦皆有显著差异（Ｐ＜０．０５～０．００１）。文献报道铜离子浓度达１．０μｇ／ｍｌ有杀死或抑制精子活动的作用，浓度为０．７μｇ／ｍｌ能使孕卵胚泡中毒。本文置ＶＣｕ１２００ＩＵＤ者第１０年时铜离子含量为１．１１μｇ／ｇ粘液湿重，第１５年为０．９１±０．１μｇ／ｇ粘液湿重，依此推测ＶＣｕ２００ＩＵＤ至少可放置１０年以上。
In this paper, flame atomic absorption spectrophotometer HITACHI-180 test set VCu200IUD women cervical mucus copper content of 267 cases. The results showed that from the first year the average copper content of 2.66 ± 0.58μg / g mucus wet weight to the 15th year dropped to 0.91 ± 0.6μg / g mucus wet weight, indicating that the copper content of cervical mucus with the placement Time is getting longer and less. 214 cases of metal ring group, the average age of cervical mucus copper content of 0.35 ± 0.08 ~ 0.56 ± 0.14μg / g mucus wet weight. The average copper content of cervical mucus in 21 cases with no device group was 0.47 ± 0.11μg / g mucus wet weight, and there was significant difference between VCu200 group and metal ring group (P <0.05-0). 001). Compared with fK in each year, there was a significant difference (P <0.05 ~ 0.001). Reported in the literature of copper ion concentration of 1.0μg / ml have the effect of killing or inhibiting sperm motility, concentration of 0.7μg / ml egg ovulation can cause poisoning. VCu1200IUD who set the first 10 years when the copper ion content of 1.11μg / g mucus wet weight, the first 15 years 0.91 ± 0.1μg / g mucus wet weight, speculated that VCu200IUD can be placed at least 10 years.