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脐尿管癌临床少见,预后不良,发病机理一般认为是脐尿管的移行上皮化生所致。临床表现主要是无痛性肉眼血尿,伴尿频尿急,尿中含有粘液及耻骨上肿块。通过CT、B超和膀胱镜等多项检查再根据脐尿管癌的诊断标准,11例中有7例患者术前作出正确诊断。2例有盆腔淋巴结转移,其中1例合并腹腔广泛转移。治疗以手术为主,采用扩大的膀胱切除术,即包括膀胱顶部、腹横筋膜和部分腹膜连同肿瘤整块切除,病理报告均为脐尿管粘液性腺癌。术后生存3例,2例术后1年,1例术后6年。5年存活率为9%。
Umbilical urinary tract cancer is rare in clinical practice and has a poor prognosis. The pathogenesis is generally believed to be caused by transitional epithelial metaplasia of urachal catheters. The main clinical manifestations are painless gross hematuria, frequent micturition with urinary urgency, and urine containing mucus and suprapubic masses. Through CT, B-ultrasound, and cystoscopy and other tests, according to the diagnostic criteria of urachal cancer, 7 of 11 patients were correctly diagnosed before surgery. Pelvic lymph node metastases were found in 2 patients, 1 of whom had extensive metastases in the abdominal cavity. Treatment was based on surgery and extended cystectomy was used, which included the top of the bladder, the transverse fascia of the abdomen, and part of the peritoneum together with the en bloc resection of the tumor. The pathological reports were urachal mucinous adenocarcinoma. There were 3 cases of postoperative survival, 2 cases of postoperative 1 year and 1 case of 6 years postoperatively. The 5-year survival rate is 9%.