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初乳中含有丰富的生长因子，可促进体外培养的ＮＩＨ－３Ｔ３细胞的ＤＮＡ合成，含０．５％（Ｖ／Ｖ）初乳的培养液与含５％小牛血清的培养液有相同的促进生长作用。初乳每毫克蛋白促细胞ＤＮＡ合成的能力比牛血清高３０倍。人初乳中生长活性物质较为丰富，含有两类生长因子──初乳酸性生长因子（ＣＡＧＦ）和初乳碱性生长因子（ＣＢＧＦ）。这两种因子对尿素和盐酸稳定，其中ＣＡＧＦ不被巯基乙醇失活，而ＣＢＧＦ可被巯基乙醇失活。ＳＤＳ－聚丙烯酰胺凝胶电泳表明，ＣＡＧＦ分子量约为６ｋＤａ，为一单体分子，ＣＢＧＦ分子量为３０ｋＤａ，是一种以二硫键共价结合的二聚体。初步推断ＣＡＧＦ为表皮生长因子样（ＥＧＦ－ｌｉｋｅ）因子；ＣＢＧＦ为血小板源生长因子样（ＰＤＧＦ－ｌｉｋｅ）因子。
Colostrum is rich in growth factors that promote the DNA synthesis of NIH-3T3 cells cultured in vitro. The medium containing 0.5% (V / V) colostrum and the 5% fetal bovine serum Promote growth. Colostrum per milligram of protein promotes cell DNA synthesis 30 times higher than bovine serum. Human colostrum is rich in active substances, which contain two types of growth factors - CAGF and CBGF. Both of these factors are stable to urea and hydrochloric acid, where CAGF is not inactivated by mercaptoethanol and CBGF can be inactivated by mercaptoethanol. SDS-polyacrylamide gel electrophoresis showed that, CAGF molecular weight of about 6kDa, is a monomer molecule, CBGF molecular weight of 30kDa, is a dimer disulfide bond covalently bound. Preliminary inference CAGF EGF-like factor; CBGF platelet-derived growth factor-like (PDGF-like) factor.