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本文打算解答的问题有两个:(1)在放射治疗中我们能把乏氧细胞忘掉吗?(2)是否有可能通过其它途径使放疗取得较大的进展?简单地讲,对第一个问题的回答是不能;对第二个问题,仅能回答或许可能。因乏氧引起的辐射抗性在X 线发明后的最初几年,人们就发现压迫皮肤可减轻X 线的皮炎反应,但直到20年代乏氧性辐射抗性才被证明。Holthusen 在1921年发现,在氮气中照射海胆卵需要较大X 线剂
There are two questions that this paper intends to answer: (1) Can we forget about hypoxic cells in radiation therapy? (2) Is it possible to make greater progress in radiotherapy through other means? Simply put, the first The answer to the question is not; for the second question, only the answer may be possible. Radiation resistance due to hypoxia In the first years after the invention of X-rays, it was found that compressing the skin can reduce the X-ray dermatitis response, but it was not until 20s that the hypoxic radiation resistance was proved. Holthusen discovered in 1921 that irradiation of sea urchin eggs in nitrogen requires larger X-ray agents