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Kaposi氏肉瘤是我国罕见的恶性肿瘤,其组织来源不清。此研究临床和病理都确诊为头皮Kaposi氏肉瘤-典型病例,通过应用多种单克隆抗体进行了细致的免疫组织化学研究(结果显示:VIM阳性,F阳性,F-8弱阳性,NSE,DES,CK和S-100均为阴性)和组织学观察。综合研究结果显示:不支持传统上该瘤血管或周围神经来源的学说。作者提出了与实验结果一致的新观点,即Kaposi氏肉瘤可能起源于纤维组织细胞。
Kaposi’s sarcoma is a rare malignancy in China and its tissue origin is unclear. This study was clinically and pathologically diagnosed as a scalp Kaposi’s sarcoma - a typical case. A detailed immunohistochemical study was performed using a variety of monoclonal antibodies (Results showed: VIM positive, F positive, F-8 weak positive, NSE, DES , CK and S-100 were all negative) and histological observations. The results of the comprehensive study indicate that the traditional doctrine of the tumor’s blood vessels or peripheral nerves is not supported. The authors proposed a new idea consistent with the experimental results that Kaposi’s sarcoma may originate from fibrous tissue cells.