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目的:分析丹参酮Ⅱ_A磺酸钠注射液引起不良反应(ADR)的原因。方法:综述文献报道中应用丹参酮Ⅱ_A磺酸钠注射液的不良反应病例,按患者年龄、性别、原患疾病、给药途径以及临床表现等进行统计、分析。结果:丹参酮Ⅱ_A磺酸钠注射液的ADR报告中,女性出现ADR的例数多于男性,临床表现多以皮疹为主,其次为寒战、发热、胸闷、头痛等。结论:医护人员应重视丹参酮Ⅱ_A磺酸钠注射液的不良反应,严格按适应证用药。
Objective: To analyze the causes of adverse reactions (ADR) induced by sodium tanshinone Ⅱ_A sodium injection. Methods: The adverse reactions of tanshinone Ⅱ_A sodium sulfonate injection in the literature were reviewed. Statistics and analysis were made according to patient’s age, gender, original disease, route of administration and clinical manifestations. Results: In the ADR report of tanshinone Ⅱ_A sodium sulfonate injection, there were more cases of ADR in women than in men. The main clinical manifestations were rash, followed by chills, fever, chest tightness and headache. Conclusion: The medical staff should pay attention to the adverse reactions of tanshinone Ⅱ_A sodium sulfonate injection, strictly according to the indications.