Refractory compounds are material with interesting properties for structural applications. However, the processing of Such material is a great challenge because of their high melting temperature and limited ductility. Mechanical alloying is a novel technique of producing refractory compounds with specific properties. Kinetical and structural peculiarities of refractory compounds and alloys obtained by mechanical alloying are discussed. However, the processing of Such material is a great challenge because of their high melting temperature and limited ductility. Kinetical and structural peculiarities of refractory compounds and alloys obtained by mechanical alloying are discussed.