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目的探讨急诊经皮冠状动脉介入治疗(PCI)对急性心肌梗死(AMI)患者血清炎症因子水平及心功能的影响。方法选取66例AMI患者作为研究对象,随机将其分为观察组与对照组,每组33例。对照组采用常规药物治疗,观察组予以PCI治疗,治疗后比较两组血清C-反应蛋白(CRP)、左心室舒张末期内径(LVED)、左室射血分数(LVEF)、二尖瓣E峰/A峰值及并发症。结果治疗后与对照组比较,观察组LVED、CRP水平均较低,而LVEF、二尖瓣E峰/A峰值水平较高,差异有统计学意义(P<0.05);观察组并发症发生率为3.03%,低于对照组的24.24%,差异有统计学意义(P<0.05)。结论采用PCI治疗AMI疗效确切,能改善患者心功能指标,降低炎症反应,值得临床推广应用。
Objective To investigate the effect of percutaneous coronary intervention (PCI) on serum levels of inflammatory cytokines and cardiac function in patients with acute myocardial infarction (AMI). Methods Sixty-six patients with AMI were selected as study subjects and randomly divided into observation group and control group, with 33 cases in each group. The patients in the control group were treated with conventional drugs and the patients in the observation group were given PCI. After treatment, the levels of C-reactive protein (CRP), left ventricular end diastolic dimension (LVED), left ventricular ejection fraction (LVEF), mitral E peak / A peak and complications. Results Compared with the control group, the LVED and CRP levels in the observation group were lower, while the LVEF and mitral E peak / A peak level were higher in the observation group (P <0.05). The complication rate in the observation group 3.03%, lower than the control group 24.24%, the difference was statistically significant (P <0.05). Conclusions The efficacy of PCI in the treatment of AMI is accurate, which can improve the cardiac function index and reduce the inflammatory reaction, which is worthy of clinical application.