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目的通过对比的方法 ,评价色甘酸钠针和特布他林针以及酮替芬片组治疗哮喘的疗效和安全性。方法将120例哮喘患者随机分成3组。酮替芬片组40例,实验组采用色甘酸钠针治疗40例,对照组采用特布他林针治疗40例。经过1周的治疗疗程,观察疗效。通过χ2检验的统计学方法 ,对各组的疗效进行统计学分析。结果在120例患者中,酮替芬片组有效率52.50%,色甘酸钠针治疗组有效率89.50%,特布他林针治疗组的有效率为80.00%。经χ2检验两两比较,色甘酸钠针治疗组的有效率均高于单独用特布他林针以及酮替芬片组,P值分别为0.005和0.001;单独用特布他林针治疗组的有效率高于酮替芬片组,两组χ2检验,P值为0.009。在三组治疗过程中,患者均未出现严重不良反应。结论色甘酸钠针治疗哮喘的效果明显好于单独用特布他林针的有效率。同时,治疗过程中的不良反应少。
Objective To compare the efficacy and safety of sodium cromolyn and terbutaline needle and ketotifen tablets in the treatment of asthma. Methods 120 patients with asthma were randomly divided into three groups. 40 cases were treated with ketotifen, 40 cases were treated with cromolyn sodium in the experimental group, and 40 cases were treated with terbutaline injection in the control group. After 1 week of treatment, observe the effect. By χ2 test of statistical methods, the efficacy of each group were statistically analyzed. Results Among the 120 patients, the effective rate of ketamine group was 52.50%, that of cromolyn sodium needle group was 89.50%, that of terbutaline group was 80.00%. The results ofχ2 test showed that the effective rates of sodium cromoglicate acupuncture group were higher than that of the combination of terbutaline and ketotifen alone, P values were 0.005 and 0.001, respectively. The effective rate is higher than ketotifen tablets, two groups χ2 test, P value was 0.009. In the three groups of treatment, patients did not have serious adverse reactions. Conclusion The efficacy of sodium cromoglica needle in the treatment of asthma is significantly better than that of terbutaline needle alone. At the same time, fewer side effects during treatment.