自1979年报导硒,维生素E治疗大骨节病有效以来,由于该报导未设对照组,对其结果有疑议,各地采用严格的实验方法进行复试后,报导干骺端有效率最高者为82.69%,其次为47.06%至52.38%等,也有报导见效果者。为揭示各地硒的防治效果之所以不同的本质问题。本文选择了各种类型的病区进行了现场实验流行病学观察,报导如下: Since selenium and vitamin E were reported to be effective in treating Kashin-Beck disease in 1979, there was no doubt about the results of this report because there was no control group in the report. After the re-examination was carried out in various places by strict experimental methods, the highest effective rate of the metaphyseal was 82.69 %, Followed by 47.06% to 52.38%, etc., there are reports of effect. In order to reveal the different selenium control effect of the essence of the problem. This article chose various types of wards field experimental epidemiological observations reported as follows: