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目的探讨女性原发性乳腺粘液腺癌的临床及组织学特征对预后的影响。方法将10 1例女性乳腺粘液腺癌患者分为 2组 :纯型组 74例 ,混合型组 2 7例。对 2组的预后与临床及组织学的关系进行了统计学分析。结果纯型组的淋巴结阳性率 (2 4 % )明显低于混合型组 (5 2 % ) (χ2 =10 4 ,P <0 0 1)。纯型组的 10年生存率 (87% )明显好于混合型组 (5 9% ) (χ2 =8 90 ,P <0 0 1) ,闭经前纯型组的 10年生存率 (89% )也明显高于混合型组 (5 0 % ) (χ2 =11 4 4 ,P <0 0 1)。结论乳腺粘液腺癌具有良好的组织学特征和预后 ,淋巴结的转移状况是影响预后的最重要因素。
Objective To investigate the clinical and histological features of female primary breast mucinous adenocarcinoma on prognosis. Methods One hundred and ten female breast mucinous adenocarcinoma patients were divided into two groups: 74 in the pure group and 27 in the mixed group. The relationship between the prognosis of two groups and the clinical and histological characteristics were statistically analyzed. Results The positive rate of lymph node (24%) in pure group was significantly lower than that in mixed group (52%) (χ2 = 104, P <0.01). The 10-year survival rate (87%) in the pure group was significantly better than that in the mixed group (59%) (χ2 = 890, P <0.01) Also significantly higher than the mixed group (50%) (χ2 = 11 4 4, P <0.01). Conclusions Mucinous adenocarcinoma has good histological features and prognosis, and lymph node metastasis is the most important factor affecting prognosis.