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3,6(二甲氨基)-二苯骈碘杂环依地酸盐(IHC-72)是近期合成的碘杂环化合物,动物实验证实它有良好的抗心律失常作用,本实验采用双微电极电压钳制术,探讨IHC-72对离体心肌细胞L-型钙通道(ICa-L)的浓度依赖性阻滞作用。用健康家兔制备浦肯野纤...
3,6 (dimethylamino) -benzodiazepine iodide Heterocyclic edetate (IHC-72) is a recently synthesized iodinated heterocyclic compound, animal experiments confirmed its good anti-arrhythmic effect, the experiment using double-micro Electrode voltage clamp technique was used to investigate the concentration-dependent blockade of IHC-72 on L-type calcium channel (ICa-L) in isolated cardiomyocytes. Preparation of Purkinje with healthy rabbits ...