环孢霉素A(CsA,商品名Sandimmun)是一种新型免疫抑制剂,已广泛用于器官移植抗排异。现又用以治疗自身免疫性疾病如红斑性狼疮、类风湿性关节炎等,近年又试用于治疗原发性肾小球肾炎,取得较好的疗效。现简述如下。作用机理CsA是由真菌产生的一种由8种氨基酸组成的环形多肽物质。它特异性抑制辅助性T细胞 Cyclosporine A (CsA, trade name Sandimmun) is a novel immunosuppressive agent that has been widely used in organ transplant rejection. Now also used to treat autoimmune diseases such as lupus, rheumatoid arthritis, etc., in recent years and try to treat primary glomerulonephritis, and achieved better results. Are summarized below. Mechanism of action CsA is a circular polypeptide consisting of eight amino acids produced by fungi. It specifically suppresses helper T cells