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Ｅ70 10是一种口服活性磺胺类抗肿瘤药 ,具有良好的抗各种皮下接种的啮齿类及人类肿瘤移植物活性。本研究的目的是评价Ｅ70 10对原位移植鼠结肠 38肿瘤的Ｃ5 7ＢＬ/ 6同基因小鼠肝转移癌及寿命的作用。将鼠结肠 38肿瘤作为一完整组织原位移植可导致Ｃ5 7ＢＬ/ 6小鼠约在 1个月
E70 10 is an orally active sulfonamide antitumor drug with good anti-invasive activity against rodents and human tumors. The purpose of this study was to evaluate the effect of E70 10 on hepatic metastases and longevity of C57BL/6 syngeneic mice orthotopically transplanted with mouse colonic 38 tumors. In situ transplantation of murine colon 38 tumors as an intact tissue can result in C5 7BL/6 mice approximately 1 month