论文部分内容阅读
目的探讨对比剂剂量及扫描时间对肝硬化患者门静脉期图像质量的影响。资料与方法 60例临床确诊的肝硬化患者随机分为3组:常规剂量常规扫描组(A)、大剂量常规扫描组(B)和大剂量延迟扫描组(C),每组20例;20例年龄相匹配的非肝硬化患者作为对照组。A组、对照组对比剂剂量1.5 ml/kg体重,B组、C组剂量为2.5 ml/kg体重,注射流率均为3.5 ml/s,A、B组及对照组门静脉期扫描时间为60 s,C组门静脉期扫描时间为70 s。测量门静脉、肝实质及肝静脉的CT值,并对图像质量进行双盲目测评分。结果 A、B、C组及对照组门静脉CT值分别为(142.16±15.25)HU、(168.29±14.63)HU、(151.42±11.96)HU和(187.73±9.45)HU;肝实质CT值分别为(87.91±11.16)HU、(98.75±10.86)HU、(93.43±11.48)HU和(109.20±5.79)HU;肝静脉CT值分别为(121.09±16.78)HU、(130.54±15.31)HU、(136.92±17.53)HU和(160.55±14.27)HU。肝硬化组门静脉、肝实质、肝静脉CT值及门静脉、肝静脉与肝实质之间的CT值差值均低于对照组(P<0.05),B组门静脉密度高于A组和C组(P<0.05),B组肝实质密度较A组和C组增高,但和C组间差别没有显著性(P>0.05)。C组相对于A组肝静脉CT值显著增加,同时肝实质密度轻度降低,两者差值明显提高(P<0.05),C组图像质量评分高于A组及B组(P<0.05)。结论肝硬化患者多期增强扫描应增大对比剂剂量,门静脉期扫描时间应适当延迟。
Objective To investigate the effect of contrast medium dose and scan time on the image quality of portal venous phase in cirrhotic patients. Materials and Methods 60 cases of clinically diagnosed patients with cirrhosis were randomly divided into 3 groups: conventional dose routine scanning group (A), high dose conventional scanning group (B) and high dose delayed scanning group (C), 20 cases each; 20 Age-matched non-cirrhotic patients served as controls. Group A, the control group, the dose of contrast agent 1.5 ml / kg body weight, group B, C dose 2.5 ml / kg body weight, injection rate was 3.5 ml / s, A, B group and control group portal vein scan time was 60 s, C group portal vein scan time was 70 s. The CT values of portal vein, liver parenchyma and hepatic vein were measured, and the blindness score of the image was evaluated. Results The CT values of portal vein in groups A, B, C and control were (142.16 ± 15.25) HU, (168.29 ± 14.63) HU, (151.42 ± 11.96) HU and (187.73 ± 9.45) HU, respectively; CT values of liver parenchyma were The mean CT values of the hepatic veins were (121.09 ± 16.78) HU, (130.54 ± 15.31) HU, (136.92 ± 0.61) HU, (98.75 ± 10.86) HU, (93.43 ± 11.48) HU and 17.53) HU and (160.55 ± 14.27) HU. The difference of CT value between portal vein, hepatic parenchyma, hepatic vein CT value and portal vein, hepatic vein and hepatic parenchyma in cirrhotic group was lower than that in control group (P <0.05). The density of portal vein in group B was higher than those in group A and C P <0.05). The density of liver parenchyma in group B was higher than that in group A and group C, but there was no significant difference between group B and group C (P> 0.05). Compared with group A, the CT value of hepatic vein in group C increased significantly and the density of hepatic parenchyma decreased slightly (P <0.05). The image quality score of group C was higher than that of group A and B (P <0.05) ). Conclusions Patients with cirrhosis should increase the dose of contrast agent in multi-phase contrast-enhanced scan. The portal venous scan time should be appropriately delayed.