基因治疗是近 10年来随着现代医学与分子生物学相结合而出现的 ,基因治疗的研究已迅速扩大到肿瘤、艾滋病、心血管病和神经系统疾病等。而且 ,基因载体 (包括质粒、病毒和脂质体等 )的研究也进展迅速 ,各种新型载体不断出现。近 10年来 ,α 病毒的多个成员已经被作为表达载体 , Gene therapy has emerged in recent 10 years with the combination of modern medicine and molecular biology. The study of gene therapy has rapidly expanded to tumors, AIDS, cardiovascular diseases and neurological diseases. Moreover, the research on gene vectors (including plasmids, viruses and liposomes) is also progressing rapidly, and various new vectors are emerging constantly. In the past 10 years, several members of the alphavirus have been used as expression vectors,