益髓胶囊可有效地抑制12月龄老年大鼠10个月自然增龄后骨基质及骨矿含量的显著减少趋势,显著改善微循环血流状态,并维持一定的性激素水平。认为该制剂是通过维持性激素水平,保持了较高的肠钙吸收率及骨吸收与骨形成的平衡,以及改善微循环,保证了骨陷窝内组织液交换和骨细胞营养从而抑制骨质丢失。 Yi-Jian Capsule can effectively inhibit the significant decrease of bone matrix and bone mineral content in aged rats aged 12 months after 10 months of natural aging, significantly improve microcirculatory blood flow, and maintain a certain level of sex hormones. The preparation is thought to maintain high levels of intestinal calcium absorption, balance of bone resorption and bone formation, and improve microcirculation by maintaining levels of sex hormones, ensuring the exchange of tissue fluid in bone lacunae and the nutrition of bone cells, thereby inhibiting bone loss.